Born in St. Petersburg, Florida, Griffin was a defensive star at UCF, where he played with his twin brother, Shaquill. Griffin was named the 2018 Peach Bowl Defensive MVP and the 2016 American Athletic Conference Defensive Player of the Year. After his college career and running the fastest 40-year dash time ever for a linebacker at the NFL Scouting Combine (4.38 seconds), Griffin was selected in the fifth round of the 2018 NFL Draft, reuniting him with Shaquill in Seattle.

Shaquem was born with amniotic band syndrome affecting his left hand, leading to an amputation when he was four. When the Seahawks selected him, he became the first one-handed player ever picked in the NFL Draft. He now shares his amazing story on overcoming adversity, accomplishing numerous achievements and doing what no one else has done before.